Speakers' presentations

Monday 22 October 2007

Prof. Charles Mgone, EDCTP Executive Director
Welcoming address
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Dr Pascoal Mocumbi, EDCTP High Representative
Building bridges between clinical trials and health care delivery in Africa
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Dr Diana Dunstan, EDCTP Assembly Chair
Linking European and African programmes: role of European member states and agencies
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Prof. Richard Adegbola, MRC The Gambia
Update on recent developments in tuberculosis clinical research in Africa
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Prof. Peter Ndumbe
Update on recent developments in HIV/AIDS clinical research in Africa
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Dr Roma Chilengi
Update on recent developments in malaria clinical research in Africa
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Dr Veronica Mulenga
CHAPAS Trials: Children with HIV in Africa: simple antiretroviral regiments - Pharmacokinetics and Adherence
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Prof. Jacques Simpore
Toward the complete eradication of mother-to-child transmission of HIV at Saint Camille Medical Centre (SCMC) - Burkina Faso
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Prof. Marleen Temmerman
Microbicides trials update
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Dr Joseph Vyankandondera
Phase III Microbicide trial preparations in Kigali, Rwanda
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Dr Kayitesi Kayitenkore
Phase I HIV-1 preventive vaccine trial in Kigali, Rwanda
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Prof. Umberto D'Alessandro
Evaluation of 4 artemisinin-based combinations for treating uncomplicated malaria in African children
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Dr Joanita Nankabirwa
Artemether-lumefantrine versus dihydroartemisinin-piperaquine for treatment of uncomplicated falciparum malaria, a randomized clinical trial at a high transmission site in Uganda
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Dr Drissa Coulibaly
Randomized controlled trial of the safety and immunogenicity of recombinant PfAMA1-FVO[25-545]) in healthy adult in Bandiagara - Mali
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Dr Sodiomon Sirima
A double blind, randomised, controlled, dose escalation phase Ib field trial in 12 to 24 month old children in Burkina Faso to evaluate the safety and immunogenicity of the Plasmodium falciparum Merozoite Surface Protein-3 Long synthetic peptide (MSP3) adjuvanted in aluminium hydroxide versus hepatitis B
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Ms Janha Ramatouli
Effects of genetic variation in CYP2C19 gene on pharmacokinetics of chlorcycloguanil
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Dr Helen McIlleron
Determining the optimal doses of antiretroviral and anti-tuberculosis medications when used in combination for the treatment of HIV/TB in co infected patients
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Dr Idefayo Adetifa
Two Interferon gamma release assays and tuberculin skin test in the diagnosis of Mycobacterium tuberculosis infection and disease in The Gambia
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Dr Pere Joan Cardona
RUTI: a new therapeutic vaccine to shorten the latent tuberculosis infection treatment
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Dr Aderemi Kehinde
Evaluation of diagnostic tools used for TB diagnosis in Ibadan, Nigeria
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Dr Smangaliso Ntshele
Recruiting volunteers to participate in a community wide preventive therapy intervention
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Tuesday 23 October 2007

Prof. Soleymane Mboup
African AIDS Vaccine Programme (AAVP)
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Dr Sibingile Walaza
Malaria Clinical Trials Alliance (MCTA)
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Dr Val Snewin
Research capacity in Africa - Wellcome Trust
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Dr Roma Chilengi
Africa Malaria Network Trust (AMANET)
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Dr Abraham Aseffa
Pan-African Bioethics Network (PABIN)
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Dr Christa Janko
The Vienna School Capacity Building Network for Africa
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Dr Abraham Alabi
Development and evaluation of high throughput, cheap and reliable assays for monitoring HIV-1 and HIV-2 viral loads in ARV programmes and clinical trials in developing countries
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Dr Didier Ekouevi
Preventing per-partum transmission of HIV-1 in Africa: tenofovir based alternatives to single dose nevirapine in the light of future treatment options
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Mr Loius Marie Yindom
The role of human leukocyte antigen (HLA) and killer immunoglobulin - like receptor (KIR) in HIV-2 infection: a key component to HIV vaccine design and its evaluation in Africa
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Mr Bornwell Sikateyo
An assessment of the understanding of the informed consent process by participants in microbicide intervention trials in Zambia
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Dr William Kilembe
Preparations for HIV vaccine research at Zambia Emory HIV Research Project (ZEHRP)
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Dr Modest Mulenga
Challenges of expediting the conduct of ethically approved phase II and III clinical trials on herbal medications in Africa
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Dr Abdoulaye Djimde
Assessment of the Public Health Benefit of artemesinin based combination therapies for uncomplicated malaria treatment on Mali
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Dr Alexis Nzila
Understanding the mechanism of piperaquine resistance
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Ms Leah Mwai
Understanding the mechanism of resistance to lumefantrine by Plasmodium falciparum
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Dr Exnevia Gomo
Research management strengthening in an emerging medical education institution: experiences of the research support centre, College of Medicine, Malawi
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Prof. Maowia Mukthar
The burden of tuberculosis in eastern Sudan: epidemiology and drug resistance patterns of Mycobacterium tuberculosis isolates
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Dr Brian Abel
BCG-induced correlates of protection against tuberculosis
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Dr Thuli Mthiyane
Reconstitution of TB antigen specific IFN-y responses in TB-HIV co-infected participants
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Dr Getnet Yimer Ali
Anti tuberculosis - anti retroviral drugs induced hepatotocity and introduction of these drugs at the level of CYP 450 metabolism
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Dr Christo van Niekerk
Clinical site and laboratory assessment project
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Dr Ashley Veldsman
An alternative consenting process: appropriate for developing countries?
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Wednesday 24 October 2007

Prof. Charles Mgone, EDCTP Executive Director
Building bridges into the future
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Dr Manuel Romaries, European Commission
EDCTP: past, present and future
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Dr Fabio Zicker
TDR's research and capacity development strategy
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Dr Nicolas Nagot
Capacity development in the conduct of clinical trials in Africa
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Mrs Matilda Mkinthi
A bioethics study of clinical research in Malawi
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Dr Francine Ntoumi
Challenges of the Multilateral Initiative on Malaria (MIM)
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Dr Hassan Mahomed
Phase III TB vaccine trial site networking (TB VACSIN)
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Dr Thomas Nyirenda
Progress on EDCTP Regional Networks of Excellence
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Dr Marie-Charlotte Bouësseau
Update on ethics on biomedical research in Africa
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Dr Richard Mhigo
Update on national regulatory development in Africa - vaccines perspective
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Dr Ramadhani Noor
Regulatory and ethics environment, difficulties and challenges
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Dr Michael Makanga
Feedback on "Enhancing capacity" session
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Dr Rosemary Musonda
Feedback on "Networks of excellence" session
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Dr Aissatou Toure
Feedback on "Regulatory and ethics" session
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