Announcement of 2016 calls for proposals
In 2016, EDCTP will launch nine calls for proposals to support clinical research and related activities. These calls are worth approximately € 138.6 M in research against poverty-related and neglected infectious diseases.
The launch of these calls follows from the approval of the EDCTP work plan for 2016 by the European Commission and the General Assembly of the EDCTP Association.
Proposals are invited for the following topics:
Vaccines for poverty-related diseases (PRDs)
The purpose of this call is to support large-scale collaborative projects which include one or more clinical trials (phase I to IV) aiming to accelerate the clinical development of new vaccines (preventive or therapeutic) against one of the PRDs. Applications must include at least one clinical trial which will be carried out in sub-Saharan Africa to test the safety, immunogenicity and/or efficacy of the vaccine(s).
Call budget: € 70M
Maximum funding: € 15M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 7 July 2016, 17:00
Close date: 13 October 2016
Stage 2 (Full proposal)
Open date (indicative): 22 December 2016
Close date (indicative): 16 March 2017
Research and clinical management of patients in PRD epidemics in sub-Saharan Africa
This call for proposals aims to support the establishment of a multidisciplinary consortium able to provide accelerated evidence for the optimal clinical management of patients and for guiding the public health response to any severe infectious outbreak caused by pathogens within the scope of the EDCTP programme with pandemic potential or that may cause significant damage to health and socio-economics in Africa (including antimicrobial-resistant pathogens).
Based on a comprehensive ‘inter-epidemic’ work programme, the consortium should ensure preparedness to perform coordinated large-scale multi-site clinical studies in response to an emerging threat. These clinical trials could include studies evaluating potential preventive or therapeutic interventions in a community or health-care setting; validation of diagnostic devices and observational clinical studies aimed at establishing the natural history and determinants of severity of the disease.
Call budget: € 10M
Maximum funding: € 10M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 7 July 2016
Close date: 29 September 2016
Stage 2 (Full proposal)
Open date (indicative): 22 December 2016
Close date (indicative): 2 March 2017
Strategic actions supporting large-scale clinical trials
The purpose of this call for proposals is to support distinct strategic actions (clinical research activities) which are part of a large-scale clinical trial that has the potential to achieve rapid advances in the clinical development of new or improved medical interventions against PRDs.
Applications for a strategic action should focus on clinical trials on PRDs in sub-Saharan Africa, and may address any disease within the scope of the EDCTP programme. Proposals that include phase III trials are encouraged.
Call budget: € 28M
Maximum funding: € 15M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 14 July 2016
Close date: 13 October 2016
Stage 2 (Full proposal)
Open date (indicative): 22 December 2016
Close date (indicative): 16 March 2017
Clinical trials and operational research studies to optimise the use of products for poverty-related diseases in mothers, newborns, children and/or adolescents
This call aims to support actions on preventive and therapeutic clinical interventions of post-registration products, as well as related behavioural studies, aimed at optimising use of new or improved products or combination of products for mothers, newborns, children and/or adolescents.
The scope of this call is limited to clinical trials and operational studies with a product focus.
Activities may include: studies on product (drugs, vaccines, microbicides and diagnostics) development, delivery, uptake and adherence; and strategies for equitable and full-scale access to diagnostics, prevention and treatment interventions. This includes community-based interventions/approaches and qualitative studies.
Call budget: € 10M
Maximum funding: € 3M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 7 July 2016
Close date: 29 September 2016
Stage 2 (Full proposal)
Open date (indicative): 12 December 2016
Close date (indicative): 2 March 2017
Strategic actions supporting health systems/services optimisation research capacities in cooperation with development assistance initiatives
The purpose of this call for proposals is to support distinct strategic actions to strengthen the capacity of health systems to effectively deliver new products and to monitor their post-market safety. This will be achieved through effective cooperation with relevant European Union initiatives including development assistance.
This should lead to better planning for the introduction of new medical interventions for PRDs; improved delivery; and, better understanding of the safety profile of and reporting mechanisms for products introduced in sub-Saharan Africa.
Call budget: € 10M
Maximum funding: € 3M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 14 July 2016
Close date: 29 September 2016
Stage 2 (Full proposal)
Open date (indicative): 8 December 2016
Close date (indicative): 2 March 2016
Ethics and regulatory capacities
The purpose of this call for proposals is to provide funding to actions that aim to support sub-Saharan African countries to establish and develop robust national medicines regulatory systems and capacities for ethical review of clinical research and use of medicinal products and technologies for use in humans. This scheme targets both National Ethics Committees (NECs) and National Regulatory Authorities (NRAs).
Call budget: € 2M
Maximum funding: € 300,000
Funding level: 100% of eligible costs
Open date: 4 August 2016
Close date: 22 November 2016
EDCTP-WHO/TDR Clinical Research and Development Fellowships
This call for proposal is a joint initiative with WHO-TDR to support researchers and key members of clinical trial research teams from low- and middle-income countries (LMICs) to acquire specific skills in clinical research and development through placements in pharmaceutical companies, PDPs and academic affiliated research institutions.
The scheme targets junior to mid-career researchers or clinical staff (clinicians, pharmacists, medical statisticians, data managers, other health researchers) who are employed by a legal entity in LMICs where they are currently working on activities in the scope of the EDCTP programme and the WHO/TDR CDF programme. Placements are for a minimum period of 12 months up to a maximum period of 18 months, following which there will be a re-integration period of 6 months (subject to the approval of a final re-integration plan).
Call budget: € 3.5M
Funding level: 100% of eligible costs
Stage 1 (Letter of Intent)
Open date: 20 October 2016
Close date: 2 February 2017
Stage 2 (Training plan – EDCTP only)
Open date (indicative): August 2017
Close date (indicative): September 2017
Senior Fellowships
This call for proposals aims to support capacity development of potential African research leaders using the train-the-trainer model and to mentor junior researchers with emphasis on hands-on research training linked to clinical trials activities conducted in sub-Saharan Africa.
The objectives of the scheme are:
- To support senior researchers to advance themselves as recognised research leaders in product development through clinical trials and related activities
- To equip senior researchers with the necessary skills and experience to train and mentor junior researchers at host institutions in sub-Saharan Africa.
Call budget: € 3M
Maximum funding: € 500,000
Funding level: 100% of eligible costs
Open date: 3 October 2016
Close date: 1 February 2017
Career Development Fellowships
This call for proposals aims to provide funding to actions that aim to support junior to mid-career researchers (“fellows”) to train and develop their clinical research skills.
The objectives are:
- To promote career development and retention of postdoctoral researchers and postgraduate medical researchers in the research field and in sub-Saharan Africa;
- To equip the fellows with the ability to establish themselves as independent researchers and with the skills to initiate and manage their own research and team at host organisations in sub-Saharan Africa.
Call budget: € 2.1M
Maximum funding: € 150,000
Funding level: 100% of eligible costs
Open date: 3 October 2016
Close date: 28 February 2017
EDCTP2 work plan 2016
The work plan describes activities under the second EDCTP programme (EDCTP2) in 2016. It provides information on EDCTP-managed calls for proposals, including the challenge, scope and expected impact, as well as supporting information about eligibility requirements and other specific conditions for applying. It also contains an overview of the Participating States’ Initiated Activities (PSIAs), i.e. activities funded and implemented directly by one or more EDCTP Participating States, which are considered an integral part of the EDCTP programme.
