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Calls for Proposals: ‘Strategic projects with major cofunding’ and ‘Improved treatment and clinical management of poverty-related diseases’

28 January 2015

Today, EDCTP published two new calls for proposals under its second programme. The call Strategic projects with major cofunding aims to provide cofunding to strategically important, large-scale research projects with the potential to achieve rapid advances in the field of PRDs and to make a significant contribution to the objectives of EDCTP2. The call for Improved treatment and clinical management of poverty-related diseases aims to provide funding to projects that aim to evaluate new or significantly improved drugs or drug regimens in humans or to optimise the efficacy and use of existing therapeutics for any of the PRDs targeted through this call. The deadline to submit letters of intent is 16 April 2015.

Strategic projects with major cofunding

The purpose of this call for proposals is to provide cofunding to strategically important, large-scale research projects with the potential to achieve rapid advances in the field of poverty-related diseases (PRDs) and to make a significant contribution to the objectives of EDCTP2.

Applications for a strategic project should focus on clinical trials, related clinical research and/or capacity building efforts on PRDs in sub-Saharan Africa, and may address any area of research within the scope of EDCTP2. Projects to conduct phase III trials and/or address research areas not covered by other open or forthcoming EDCTP2 calls for proposals in 2014 or 2015 are encouraged. The requested EDCTP contribution shall neither exceed 50% of the total cost of the activity nor €10 million; the total cost of the activity shall not be less than €3 million. Applicants must demonstrate financial commitment from other funders (Participating States and/or third parties) to cofund the proposed project.

Projects funded under this Call for Proposals will contribute to increased international cooperation among research groups and public and private funders; catalyse research synergies; leverage resources and investments; and maximise the impact of global research in PRDs.

Two-stage application procedure:

Stage 1 – Letter of Intent
Opening date: 28 January 2015
Deadline for submission: 16 April 2015

Stage 2 – Full proposal
Selection results will be available by 9 July 2015
Deadline for submission: 30 September 2015
Type of grant: Research & Innovation Action (RIA)
Funding level: 50% of eligible costs
Expected number of grants: 2-5

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Improved treatment and clinical management of poverty-related diseases

The purpose of this call for proposals is to provide funding to projects that aim to evaluate new or significantly improved drugs or drug regimens in humans or to optimise the efficacy and use of existing therapeutics for any of the poverty-related diseases (PRDs), including co-infections of PRDs.

Proposals should include one or more clinical trial(s) (phase I-IV) of therapeutics for PRDs to be conducted in sub-Saharan Africa. Proposals for conducting phase II and/or III clinical trials are encouraged. The requested EDCTP contribution per activity shall not exceed €15 million.

Projects funded under this call for proposals should lead to improvements in public health as a result of policy change at national, regional or global level, through evidence-based formulation and implementation of treatment guidelines and/or lead to the advancement of product candidates through the clinical pipeline or registration or pre-qualification of new products.

Two-stage application procedure:

Stage 1 – Letter of Intent
Opening date: 28 January 2015
Deadline for submission: 16 April 2015

Stage 2 – Full proposal
Selection results will be available by 9 July 2015
Deadline for submission: 30 September 2015
Type of grant: Research & Innovation Action (RIA)
Call budget: 35M Euros
Funding level: 100% of eligible costs
Expected number of grants: 3-5

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