24 August 2015

European and African clinical research on poverty-related and neglected diseases, 2003-2011 - a bibliometric analysis

On 11 August 2015 PLOS neglected tropical diseases published the research article ‘Bibliometric assessment of European and sub-Saharan African research output on poverty-related and neglected infectious diseases from 2003-2011’ by authors from EDCTP and Thomson Reuters. Today, EDCTP publishes the…

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10 August 2015

EDCTP Annual Report 2014 available online

The online summary EDCTP Annual Report 2014 “Starting EDCTP2” is now available on the website. It offers an updated overview of all EDCTP projects of the first programme and describes the efforts to prepare for the second programme (EDCTP2) which…

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14 July 2015

Dr Michael Makanga designated as next EDCTP Executive Director

During its last meeting, the General Assembly of the European & Developing Countries Clinical Trials Partnership (EDCTP) selected Dr Michael Makanga to succeed Professor Charles Mgone as Executive Director. Prof. Mgone, who has been Executive Director for eight years, had…

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24 April 2015

World Malaria Day 2015: funding research to close the gaps

According to the WHO World Malaria Report 2014, 198 million cases of malaria occurred globally in 2013 and the disease led to 584,000 deaths. The burden is heaviest in sub-Saharan Africa, where an estimated 90% of all malaria deaths occur….

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24 March 2015

World Tuberculosis Day 2015

In May 2014, at the World Health Assembly, governments agreed on an ambitious new 20-year (2016-2035) strategy to end the global TB epidemic. According to the Stop TB Partnership “there is a critical need to address weaknesses in countries’ health…

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19 March 2015

New funding to increase capacity for Ebola outbreak research

Strengthening sub-Saharan African research capacity during infectious disease emergency outbreaks

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12 March 2015

Published: Proceedings and video report of the High-Level Launch Event for EDCTP2

Download the report (PDF)

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10 March 2015

EDCTP-funded project REMSTART finds new approach to HIV management to have reduced deaths by 28 per cent

Researchers from the REMSTART team – led by Dr Saidi Egwaga of the Tanzanian Ministry of Health and Social Welfare and Shabbar Jaffar, Professor of Epidemiology at the London School of Hygiene & Tropical Medicine – conducted a randomised trial…

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4 March 2015

EDCTP2 work plan for 2014 now available online

The first annual work plan of the second programme of the European & Developing Countries Clinical Trials Partnership (EDCTP2) describes activities under EDCTP2 launched in 2014. It provides information on EDCTP Calls for Proposals, including the challenge, scope and expected…

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26 February 2015

PanACEA MAMS-TB-01 trial: ‘high-dose rifampicin may help shorten TB treatment’

The MAMS-TB-01 trial enrolled 365 patients from 7 sites in Tanzania and South Africa in only 11 months. It is the first of several TB treatment regimen trials which will use the same innovative adaptive clinical trial design that allows…

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28 January 2015

Calls for Proposals: ‘Strategic projects with major cofunding’ and ‘Improved treatment and clinical management of poverty-related diseases’

Today, EDCTP published two new calls for proposals under its second programme. The call Strategic projects with major cofunding aims to provide cofunding to strategically important, large-scale research projects with the potential to achieve rapid advances in the field of…

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19 December 2014

EC Commissioner Carlos Moedas and Gulbenkian Foundation sign collaboration memorandum

This coincides with the prepublication today of an EDCTP 2015 Call for proposals aimed at strengthening the ethics and regulatory capacity in sub-Saharan Africa. This call will be a collaboration between EDCTP and the Calouste Gubenkian Foundation.

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19 December 2014

Preannouncement of 2015 Calls for Proposals

The purpose of this forthcoming call for proposals is to provide funding to projects that aim to evaluate new or significantly improved drugs or drug regimens in humans or to optimise the efficacy and use of existing therapeutics for any…

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17 December 2014

Call for proposals – Maximising the impact of EDCTP research: translation of research results into policy and practice

Go directly to Call text

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2 December 2014

New Call for Proposals: Diagnostic tools for poverty-related diseases

The purpose of this call is to invest in projects aiming to validate the clinical performance and/or implementation of new or improved diagnostic tools and technologies for detection of any of the poverty-related diseases, including as co-infections. These tools and…

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1 December 2014

New EDCTP programme celebrated in Cape Town, South Africa on 2 December 2014

The meeting will offer a full day of reflection and discussion on overarching topics regarding the new programme. Opening addresses will be delivered by: Naledi Pandor, Minister of Science & Technology of South Africa Mr Carlos Moedas, the European Commissioner…

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17 November 2014

Forum Proceedings and Forum video published

The Proceedings of the Seventh EDCTP Forum, held in Berlin, Germany from 30 June to 2 July 2014, are published on the EDCTP website today. The report gives a detailed overview of the research results presented and highlights of discussions…

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6 November 2014

Scholarships for MSc programma in vaccinology in Siena, Italy

The University of Siena Medical School, Novartis Vaccines and Diagnostics, Novartis Vaccines Institute for Global Health (NVGH), and the ADITEC (Advanced Immunization Technologies) programme invite applications for the Master Programme in Vaccinology and Pharmaceutical Clinical Development (IV edition 2015) commencing…

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31 October 2014

EDCTP and TDR offer first joint Clinical R&D Fellowships

A total of 25 fellowships is available for this call; 20 product development organisations have offered to host fellows. The host organisations will train individuals to develop specialist product development skills not readily taught in academic centres or public research…

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23 October 2014

New drug combination could improve adherence to tuberculosis treatment

A novel combination of the drugs rifapentine and moxifloxacin can reduce the number of tablets to be taken by patients from 360 to 140 (administered once a week) over the six-month tuberculosis treatment period. This reduction may help patients to…

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24 September 2014

Mefloquine not recommended as alternative drug for malaria prevention treatment in pregnancy

The results of two large randomised controlled trials conducted in Africa that tested mefloquine, a drug for malaria prevention in HIV-negative and HIV-positive pregnant women, were published in the PLOS Medicine on 23 September 2014. The results showed that mefloquine…

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23 September 2014

Proceedings of the EDCTP stakeholder meeting on capacity development published

The European & Developing Countries Clinical Trials Partnership (EDCTP) has published its report of the Stakeholder meeting on capacity development today. The meeting was held in Berlin, Germany, on 3 July 2014, as part of the preparations for the second…

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19 September 2014

Current state of health research on poverty-related diseases in sub-Saharan Africa

Today, the European & Developing Countries Clinical Trials Partnership (EDCTP), RAND Europe and Baird’s CMC have published a report on the current state of health research and national funding commitments for HIV/AIDS, tuberculosis, malaria and neglected infectious diseases in sub-Saharan…

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8 September 2014

REMoxTB trial results confirm moxifloxacin safety but not shortened tuberculosis treatment

Prof. Charles Mgone, EDCTP Executive Director: “A shorter treatment regimen would have great significance for individual patients and TB care programmes alike. Unfortunately, this goal has not been achieved by the REMoxTB trial. However, it demonstrates what can be achieved…

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8 September 2014

Launch of the second EDCTP programme against poverty-related diseases in Africa

The high-level event expects to welcome approximately 200 delegates, including African and European government representatives, major research funders, scientists, industry representatives and other experts in the field. The event will take place at the Vineyard Hotel in Cape Town. Participation…

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1 September 2014

TAM-TB: New sputum-independent diagnostic tool for tuberculosis in children

Today, The Lancet Infectious Diseases published the results of a sputum-independent assay developed in Tanzania that is able to diagnose active tuberculosis in children. The T cell activation (TAM)-TB) assay is the first immunodiagnostic tool which can detect active tuberculosis…

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17 July 2014

Results of trial to assess second-line therapy in HIV patients in Africa published

The combination of a boosted protease inhibitor (lopinavir) with two nucleoside reverse-transcriptase inhibitors (NRTIs) is a feasible second-line therapy for HIV patients in Africa. These are the results of the EDCTP-funded EARNEST trial, coordinated by Prof. Peter Mugyenyi (Joint Clinical…

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27 June 2014

EDCTP Annual Report 2013 available online

The interactive EDCTP Annual Report 2013 “The First Decade” is now available on the website. It gives access to the complete Annual Report 2013 in three languages namely English, French and Portuguese (PDF downloads). The component of Financial Statements for…

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20 May 2014

International clinical trials day: EDCTP extends its gratitude to all clinical trial volunteers

Clinical trials depend on the participation of volunteers, both the healthy and those suffering from disease. Their dedication based on free and well informed consent is critical to achieve the objectives of clinical trials. After a decade of funding clinical…

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6 May 2014

Dr Pascoal Mocumbi takes his leave as the EDCTP High Representative

With the end of the first programme nearing, Dr Pascoal Mocumbi has taken his leave as the High Representative of the European & Developing Countries Clinical Trials Partnership (EDCTP). Dr Mocumbi, Prime Minister of Mozambique from 1994 to 2004, joined…

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