Clinical trials to reduce health inequities in pregnant women, newborns and children – 2017

This call aims to accelerate the adaption and/or optimisation of treatment and prevention products (excluding vaccines) for PRDs in sub-Saharan Africa for use in pregnant women, newborns and/or children. Proposals were to focus on adaption of existing medicines, including off-patent products, to the specific needs of pregnant women, newborns and/or children.
Call identifier: RIA2017MC

Clinical evaluation of artesunate + amodiaquine + atovaquone – proguanil tri-therapy for malaria treatment in African children

Kwame Nkrumah University of Science and Technology (KNUST), Kumasi, Ghana with partners from Benin, Burkina Faso, France, Gabon, Germany, and Mali
Project coordinator: Dr. Oumou Maiga-Ascofare (KNUST), Ghana
Starting date: 01 March 2019
Duration: 48 months
EDCTP grant amount: EUR 7,642,364
Grant agreement: RIA2017MC-2022

A cluster randomised trial to evaluate the effectiveness of household alcohol-based hand rub for the prevention of sepsis, diarrhoea and pneumonia in Ugandan infants

University of Liverpool (UoL), Liverpool, United Kingdom with partners from Norway, Uganda, and United Kingdom
Project coordinator: Prof. Andrew Weeks (UoL), United Kingdom
Starting date: 01 February 2019
Duration: 60 months
EDCTP grant amount: EUR 5,977,299
Grant agreement: RIA2017MC-2029

Empirical treatment against cytomegalovirus and tuberculosis in severe pneumonia in HIV-infected infants: a randomised controlled clinical trial

Servicio Madrileña de Salud (SERMAS), Madrid, Spain with partners from Côte d’Ivoire, France, Italy, Mozambique, the Netherlands, Spain, Uganda, United Kingdom, Zambia, and Zimbabwe
Project coordinator: Dr Pablo Rojo (Hospital 12 de Octubre /Complutense University), Madrid, Spain
Starting date: 01 February 2019
Duration: 60 months
EDCTP grant amount: EUR 7,680,619
Grant agreement: RIA2017MC-2013

Webnews: Lincoln Joins Major International HIV Trial

Efficacy and safety of a newly registered artemisinin-based combination (pyronaridine-artesunate – Pyramax®) for the treatment of uncomplicated malaria in African pregnant women

Université des sciences, des techniques et des technologies de Bamako (USTTB), Bamako, Mali with partners from Democratic Republic of the Congo, Mozambique, Netherlands, Spain, and United Kingdom
Project coordinator: Dr Kassoum Kayentao
Starting date: 01 March 2019
Duration: 60 months
EDCTP grant amount: EUR 7,085,862
Grant agreement: RIA2017MC-2025