Diagnostic tools for poverty-related diseases – 2018

The call supports projects to validate the clinical performance and/or implementation of new or improved diagnostic tools and technologies for the detection of any of the poverty-related diseases, including co-infections. The investigated tools and technologies should improve the performance of diagnosis, prediction, monitoring, intervention or assessment of therapeutic response, with a significant impact on clinical decision and health outcomes. Projects focus on late-stage development (e.g. evaluation and/or demonstration phase trials) or implementation studies in sub-Saharan Africa.

Call identifier: RIA2018D

DIAGMAL
Phase III evaluation of an innovative simple molecular test for the diagnosis of malaria in different endemic and health settings in sub-Saharan Africa

Academisch Medisch Centrum bij de Universiteit van Amsterdam (Amsterdam UMC), Amsterdam, the Netherlands, with partners in Burkina Faso, Ethiopia, Kenya, Namibia, Sudan, and the United Kingdom.
Project coordinator: Dr Henk Schallig (Amsterdam UMC)
Starting date: 01 December 2019
Duration: 48 months
EDCTP grant amount: EUR 2,999,499
Grant agreement: RIA2018D-2496

LAMP4Yaws
Clinical evaluation of a loop-mediated isothermal amplification test for Treponema pallidum pertenue: A diagnostic tool to support yaws eradication

London School of Hygiene & Tropical Medicine (LSHTM), London, United Kingdom, with partners in Cameroon, Côte d’Ivoire, Germany, Ghana, and Spain.
Project coordinator: Dr Michael Marks (LSHTM)
Starting date: 01 January 2020
Duration: 36 months
EDCTP grant amount: EUR 2,907,871
Grant agreement: RIA2018D-2495

SeroSelectTB
Evaluation of the feasibility, accuracy, and effect of a rapid point-of-care serological triage test for active TB (SeroSelectTB) in high burden, HIV-endemic African settings: a multi-centre, parallel-group, randomised, controlled trial

Norwegian Institute of Public Health (NIPH), Oslo, Norway, with partners in Austria, Ethiopia, France, Germany, the Netherlands, South Africa, and Tanzania.
Project coordinator: Prof. Carol Holm-Hansen (NIPH)
Starting date: 01 January 2020
Duration: 48 months
EDCTP grant amount: EUR 2,998,559
Grant agreement: RIA2018D-2493

TB TRIAGE+
Community-based tuberculosis triage testing after symptom screening in hard-to-reach African populations: CAD4TB versus C-reactive protein (TB TRIAGE+)

Swiss Tropical and Public Health Institute, Basel, Switzerland with partners in Belgium, Germany, Lesotho, the Netherlands, South Africa, and Switzerland.
Project coordinator: Dr Klaus Reither
Starting date: 01 January 2020
Duration: 48 months
EDCTP grant amount: EUR 3,191,622
Grant agreement: RIA2018D-2498

TriageTB
Field evaluation of a point-of-care triage test for active tuberculosis

Stellenbosch University (SUN), Stellenbosch, South Africa, with partners in Germany, the Netherlands, Switzerland, Uganda, and the United Kingdom.
Project coordinator: Prof. Gerhard Walzl (SUN)
Starting date: 01 October 2019
Duration: 48 months
EDCTP grant amount: EUR 3,291,740
Grant agreement: RIA2018D-2499