Clinical trials to reduce health inequities in pregnant women, newborns and children – 2016

The objective of this call is to accelerate the adaption and/or optimisation of treatment and prevention products (excluding vaccines) for PRDs in sub-Saharan Africa for use in pregnant women, newborns and/or children. This call is restricted to the following diseases: HIV, malaria, tuberculosis, diarrhoeal diseases, and lower respiratory infections.

Call identifier: RIA2016MC

See the corresponding call for proposals

Combined HIV African prevention study:  on-demand Truvada and F/TAF pre-exposure prophylaxis to protect adolescents from HIV

King’s College London (KCL), United Kingdom with partners from South Africa, Sweden, Uganda, United Kingdom, and Zimbabwe
Project Coordinator: Dr Julie Fox, KCL, United Kingdom
Starting date:
 1 April 2018
Duration: 48 months
Grant amount: EUR 2,999,999
Grant agreement: RIA2016MC-1616
Project web pages

Fast and reliable easy-to-use-diagnostics for eliminating Bilharzia in young children and mothers

Academisch Ziekenhuis Leiden (LUMC), Leiden, the Netherlands with partners from Gabon, Germany, Madagascar, and Spain
Project Coordinator: Dr Govert J. van Dam, LUMC, the Netherlands
Starting date:
 1 February 2018
Duration: 60 months
Grant amount: EUR 2,999,409
Grant agreement: RIA2016MC-1626

Life study
Neonatal HIV early infant diagnosis (EID) versus standard-of-care EID – Impact on infant health: a feasibility study of point-of-care testing at birth versus at 6 weeks of age on the uptake of ART and infant prophylaxis, and on rate of infant survival, morbidity and retention in care

Instituto nacional de Saude (INS), Maputo, Mozambique with partners from Germany, Portugal, Tanzania, and the United States. 
Project Coordinator: Dr Ilesh Jani, INS, Mozambique
Starting date:
 1 June 2018
Duration: 60 months
Grant amount: EUR 2,965,733
Grant agreement: RIA2016MC-1615

Improving maternal and infant health by reducing malaria risks in African women: evaluation of the safety and efficacy of dihydroartemisinin-piperaquine for intermittent preventive treatment of malaria in HIV-infected pregnant women

Fundación Privada Instituto de Salud Global Barcelona (ISGlobal) with partners from Austria, Gabon, Germany, and Mozambique 
Project Coordinator: Prof. Clara Menéndez Santos, ISGlobal, Spain
Starting date:
 1 March 2018
Duration: 60 months
Grant amount: EUR 2,985,000
Grant agreement: RIA2016MC-1613
MAMAH project website; ISGLobal Webpage; ISGlobal Blogpost

Prevention of mother-to-child transmission of HIV-1: program evaluation and innovative rescue intervention integrated in the expanded program of immunization

Institut national de la santé et de la recherche médicale (Inserm), Paris, France with partners from Burkina Faso, Norway, and Zambia
Project Coordinator: Prof. Philippe van de Perre, Inserm – Montpellier University, France
Starting date:
 1 May 2018
Duration: 36 months
Grant amount: EUR 2,999,634
Grant agreement: RIA2016MC-1617
Project description on ERA LEARN website

RaPaed TB
Rapid and accurate diagnosis of paediatric TB

Ludwig Maximilians Universität München (LMU), Germany with partners from Australia, Germany, Malawi, Mozambique, South Africa, Sweden, Switzerland, and Tanzania 
Project Coordinator: Dr Norbert Heinrich, LMU, Germany
Starting date:
 1 February 2018
Duration: 54 months
Grant amount: EUR 2,999,632
Grant agreement: RIA2016MC-1623

Vulnerable population tuberculosis anti-retroviral

University of Liverpool, Liverpool, United Kingdom with partners from Italy, South Africa, and Uganda
Project Coordinator: Dr Catriona Waitt, University of Liverpool, United Kingdom
Starting date:
 1 February 2018
Duration: 60 months
Grant amount: EUR 2,058,002
Grant agreement: RIA2016MC-1606
Liverpool University news item 25 April 2018