Diagnostic tools for poverty-related diseases – 2018

The call supports projects to validate the clinical performance and/or implementation of new or improved diagnostic tools and technologies for the detection of any of the poverty-related diseases, including co-infections. The investigated tools and technologies should improve the performance of diagnosis, prediction, monitoring, intervention or assessment of therapeutic response, with a significant impact on clinical decision and health outcomes. Projects focus on late-stage development (e.g. evaluation and/or demonstration phase trials) or implementation studies in sub-Saharan Africa.

 

Call identifier: RIA2018D

DIAGMAL
Phase III evaluation of an innovative simple molecular test for the diagnosis of malaria in different endemic and health settings in sub-Saharan Africa

Academisch Medisch Centrum bij de Universiteit van Amsterdam (Amsterdam UMC), Amsterdam, the Netherlands, with partners in Burkina Faso, Ethiopia, Kenya, Namibia, Sudan, and the United Kingdom
Project coordinator: Dr Henk Schallig (Amsterdam UMC)
Starting date: 01 December 2019
Duration: 48 months
EDCTP grant amount: EUR 2,999,499
Grant agreement: RIA2018D-2496
Project website

ERASE-TB
Early risk assessment in TB contacts by new diagnostic tests

Ludwig Maximilians Universitaet Muenchen (LMU), Munich, Germany, with partners in Mozambique, Sweden, Tanzania, the United Kingdom, and Zimbabwe
Project coordinator: Dr Norbert Heinrich (LMU)
Starting date: 01 May 2020
Duration: 48 months
EDCTP grant amount: EUR 3,324,698
Grant agreement: RIA2018D-2508

LAMP4Yaws
Clinical evaluation of a loop-mediated isothermal amplification test for Treponema pallidum pertenue: A diagnostic tool to support yaws eradication

London School of Hygiene & Tropical Medicine (LSHTM), London, United Kingdom, with partners in Cameroon, Côte d’Ivoire, Germany, Ghana, and Spain
Project coordinator: Dr Michael Marks (LSHTM)
Starting date: 01 January 2020
Duration: 36 months
EDCTP grant amount: EUR 2,907,871
Grant agreement: RIA2018D-2495
Project website

PreFIT
Predicting the future: incipient tuberculosis

Stichting Amsterdam Institute for Global Health and Development (AIGHD), Amsterdam, the Netherlands, with partners in Mozambique, South Africa, Spain, Switzerland, and Uganda
Project coordinator: Prof. Frank Cobelens (AIGHD)
Starting date: 01 February 2020
Duration: 48 months
EDCTP grant amount: EUR 3,299,454
Grant agreement: RIA2018D-2509

SeroSelectTB
Evaluation of the feasibility, accuracy, and effect of a rapid point-of-care serological triage test for active TB (SeroSelectTB) in high burden, HIV-endemic African settings: a multi-centre, parallel-group, randomised, controlled trial

Norwegian Institute of Public Health (NIPH), Oslo, Norway, with partners in Austria, Ethiopia, France, Germany, the Netherlands, South Africa, and Tanzania
Project coordinator: Prof. Carol Holm-Hansen (NIPH)
Starting date: 01 January 2020
Duration: 48 months
EDCTP grant amount: EUR 2,998,559
Grant agreement: RIA2018D-2493
Project website

STooL4TB
Evaluating a new stool-based qPCR for diagnosis of tuberculosis in children and people living with HIV

Fundación Privada Instituto de Salud Global Barcelona (ISGlobal), Barcelona, Spain, with partners in Eswatini, Germany, Mozambique, the Netherlands, and Uganda
Project coordinator: Dr Alberto Garcia Basteiro
Starting date: 01 October 2020
Duration: 48 months
EDCTP grant amount: EUR 2,999,989
Grant agreement: RIA2018D-2511

TriageTB
Field evaluation of a point-of-care triage test for active tuberculosis

Stellenbosch University (SUN), Stellenbosch, South Africa, with partners in Germany, the Netherlands, Switzerland, Uganda, and the United Kingdom
Project coordinator: Prof. Gerhard Walzl (SUN)
Starting date: 01 October 2019
Duration: 48 months
EDCTP grant amount: EUR 3,291,740
Grant agreement: RIA2018D-2499
Project website

XACT-III
A randomised control trial to evaluate a scalable active case-finding intervention for tuberculosis using a point-of-care molecular tool (Xpert Omni)

The University of Cape Town Lung Institute (Pty) Ltd., Cape Town, South Africa, with partners in Italy, the United Kingdom and Zimbabwe
Project coordinator: Prof. Keertan Dheda
Starting date: 01 April 2020
Duration: 48 months
EDCTP grant amount: EUR 754,774
Grant agreement: RIA2018D-2505

XACT-IIIB
A randomised control trial to evaluate a scalable active case-finding intervention for tuberculosis using a point-of-care molecular tool (Xpert Omni)

The University of Cape Town Lung Institute (Pty) Ltd., Cape Town, South Africa, with partners in Mozambique, the Netherlands, The United Kingdom, and Zambia
Project coordinator: Prof. Keertan Dheda
Starting date: 01 April 2020
Duration: 48 months
EDCTP grant amount: EUR 2,920,284
Grant agreement: RIA2018D-2505