Strategic actions supporting large-scale clinical trials – 2015

The purpose of this call for proposals is to support distinct strategic clinical research activities that are part of a large-scale clinical trial that has the potential to achieve rapid advances in the clinical development of new or improved medical interventions against poverty-related infectious diseases within the scope of the EDCTP programme.

Call identifier: RIA2015S

See the corresponding call for proposals

A randomised controlled trial to assess the safety, acceptability and pharmacokinetics of a sustained-release tenofovir-alafenamide sub-dermal implant for HIV prevention in women

Centre for the Aids Programme of Research in South Africa (CAPRISA) (South Africa) with partners from Ireland and France
Grant agreement: SRIA-2015-1061
Project coordinator: Prof Salim S. Abdool Karim, CAPRISA, South Africa
Starting date:
1 January 2017
Duration: 60 months
Total project value: EUR 19,814,470
EDCTP grant amount: EUR 9,814,470
Cofunding from: to be confirmed

Globally relevant AIDS vaccine Europe-Africa trials partnership

University of Oxford (United Kingdom) with partners from Kenya, The Netherlands, Uganda, United Kingdom, United States, and Zambia
Grant agreement: SRIA-2015-1066
Project Coordinator:
Prof. Tomáš Hanke, University of Oxford, United Kingdom
Starting date:
1 January 2017
Duration: 60 months
Total project value: EUR 16,810,411
EDCTP grant amount: EUR 7,092,010
Cofunding from: International AIDS Vaccine Initiative (IAVI Inc., USA); University of Oxford (UK); and Imperial College of Science, Technology and Medicine (University of London, UK)
Grantee press release

Using biomarkers to predict TB treatment duration

Stellenbosch University (South Africa) with partners from Germany, The Netherlands, South Africa, and the United Kingdom
Grant agreement: SRIA-2015-1065
Project coordinator:
Prof. Gerhard Walzl, Stellenbosch University, South Africa
Starting date:
1 February 2017
Duration: 66 months
Total project value: EUR 25,222,905
EDCTP grant amount: EUR 7,722,491
Co-funding from: Bill & Melinda Gates Foundation (USA); National Institutes of Health (USA); National Institute of Allergy & Infectious Diseases (USA)