Vaccines for diarrhoeal diseases or lower respiratory tract infections (2018)

This call for proposals supports clinical trials that can accelerate the development of vaccines for diarrhoeal infections and lower respiratory tract infections in sub-Saharan Africa. Proposals include one or more clinical trials (phase I to III) in sub-Saharan Africa for vaccine candidates towards one or more of the following pathogens: 1) diarrhoeal diseases: Shigella and/or enterotoxigenic E. coli (ETEC); or 2) lower respiratory tract infections: respiratory syncytial virus (RSV) or Group B streptococcus (GBS).

Call identifier: RIA2018V

PREPARE
Prevention of invasive Group B Streptococcus disease in young infants: a pathway for the evaluation & licensure of an investigational maternal GBS vaccine

St George’s Hospital Medical School (SGUL), London, United Kingdom, with partners in Denmark, France, Italy, the Netherlands, South Africa, Uganda, the United Kingdom, and the United States of America.
Project coordinator: Dr Kirsty Le Doare
Starting date: 01 October 2019
Duration: 60 months
EDCTP grant amount: EUR 9,995,744
Grant agreement: RIA2018V-2304

ShigOraVax
Early clinical development of an oral Shigella vaccine through phase II study in Africa

European Vaccine Initiative EWIV (EVI), Heidelberg, Germany, with partners in Burkina Faso, India, the Netherlands, Sweden, and Zambia
Project coordinator: Dr Hilde Depraetere (EVI, Germany)
Starting date: 01 October 2019
Duration: 60 months
EDCTP grant amount: EUR 8,604,333
Grant agreement: RIA2018V-2308