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Stakeholder meeting on tuberculosis and other mycobacterial infections

Start date: 28 October 2013, 09:00
End date: 29 October 2013, 17:00
Location: Paris, France
Type of event: EDCTP stakeholder meeting
Scope: Tuberculosis

The objective of the stakeholder meeting on tuberculosis and other mycobacterial infections was to assess the current status in the field and to identify the key research areas, current opportunities and barriers to progress.

Participants at the meeting included researchers from academia, representatives of product development partnerships (PDPs) and pharmaceutical industry, policy makers, funding agencies and other like-minded organisations.

Amongst the topics to be discussed were:

  • TB diagnostics, in particular for paediatric and latent tuberculosis
  • TB vaccines
  • TB drugs: testing of novel drugs or drug combinations for treatment of drug-sensitive and multi-drug resistant tuberculosis
  • Capacity building and trial site requirements for conducting clinical trials on tuberculosis
  • TB co-infections, in particular HIV
  • NIDs (Buruli ulcer, leprosy)

Expected outcomes of the meeting

The meeting report was published on the EDCTP website with an open call for comments and feedback from the research community in response to the report. The expected output is a series of recommendations to shape EDCTP strategy for supporting tuberculosis research in the second programme, such as:

  • Priority research topics for calls for proposals
  • Proposals for development of cooperative projects
  • Products in the pipeline for evaluation by EDCTP
  • Focused capacity building initiatives
  • Proposals for funding partnerships

Background reading material

  1. WHO Global TB report 2012
  2. Tuberculosis vaccines: a strategic blueprint for the next decade
  3. PDP portfolios
  4. Research Questions and Priorities for Tuberculosis: A Survey of Published Systematic Reviews and Meta-Analyses (PLoS One. 2012; 7(7): e42479. doi: 10.1371/journal.pone.0042479)
  5. Clinical Research and Development of Tuberculosis Diagnostics: Moving From Silos to Synergy (Nahid P, Kim PS, Evans CA, et al. Clinical research and development of tuberculosis diagnostics: moving from silos to synergy. J Infect Dis. 2012 May 15;205 Suppl 2:S159–68)
  6. Which New Diagnostics for Tuberculosis, and When? (Cobelens, Frank, et al. “Which New Diagnostics for Tuberculosis, and When?.” Journal of Infectious Diseases 205.suppl 2 (2012): S191-S198)
  7. Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go? (Ottenhoff THM, Kaufmann SHE (2012) Vaccines against Tuberculosis: Where Are We and Where Do We Need to Go? PLoS Pathog 8(5): e1002607. doi:10.1371/journal.ppat.1002607)

 

Presentations

  • Professor Jean-François Delfraissy, Director of the French National Agency for Research on AIDS and Viral Hepatitis (ANRS)
    Opening address
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  • Dr Gabrielle Breugelmans, EDCTP North-North Networking Manager
    Plans and Progress towards EDCTP2
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  • Professor Gavin Churchyard, Aurum Institute
    Tuberculosis & mycobacterial infections: recent advances and research priorities
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  • Dr Catharina Boehme, FIND
    TB Diagnostics: Progress, needs, pipeline
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  • Ms Shiva Dustdar, European Investment Bank (EIB)
    EIB Advisory Considerations – Global TB Vaccine Partnership
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  • Professor Stefan Kaufmann, Max Planck Institute for Infection Biology
    Vaccine Portfolio for TB and Beyond
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  • Dr Richard Hafner, National Institutes of Health/National Institute of Allergy and Infectious Diseases, NIH/NIAID
    Global drugs portfolio innovation in TB therapeutics research
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  • Professor Andreas Diacon, Task Applied Science
    Treatment II: Clinical Management of Tuberculosis and Mycobacterial Infections: Tuberculosis
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  • Professor Diana Lockwood, London School of Hygiene and Tropical Medicine (LSHTM)
    Current management of Leprosy
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  • Dr Mark Wansbrough-Jones, St George’s, University of London (SGUL)
    Buruli ulcer
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  • Dr Christian Lienhardt, WHO Global TB Programme
    Control and implementation research
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