Strategic actions supporting large-scale clinical trials – 2017

This Call for proposals is to support strategic actions (clinical research activities) that are part of a large-scale clinical trial with the potential to achieve rapid advances in the clinical development of new or improved medical interventions (drugs, diagnostics, vaccines, microbicides) for poverty-related diseases (PRDs).

Call identifier: RIA2017S

See the corresponding call for proposals

CAP012 SAMBA Trial
CAPRISA 012: Phase I/II trial of subcutaneous administration of monoclonal broadly-neutralising antibodies

Centre for the Aids Programme of Research in South Africa (CAPRISA), Durban, South Africa, with partners from France, Netherlands, and Zambia
Project coordinator: Prof. Salim Abdool Karim (CAPRISA, Durban, South Africa)
Starting date:
 1 January 2019
Duration: 60 months
EDCTP grant amount: EUR 9,254,000
Grant agreement: RIA2017S-2008

Close the gap, increase access, provide adequate therapy

Foundation for Innovative New Diagnostics (FIND), Geneva, Switzerland, with partners from Ethiopia, Germany, Italy, Mozambique, South Africa, Spain, Switzerland, and Tanzania
Project coordinator: Dr Samuel Schumacher (FIND, Geneva, Switzerland)
Starting date:
 1 September 2019
Duration: 42 months
EDCTP grant amount: EUR 5,975,984
Grant agreement: RIA2017S-2007
Project website

ETEC Vaccine Efficacy
Field studies of an oral whole-cell ETEC vaccine candidate in African toddlers and children: Assess efficacy and set parameters for pivotal phase III trials

Scandinavian Biopharma Holding AB (SBH), Solna, Sweden, with partners from Finland, Sweden, United Kingdom, and Zambia
Project coordinator: Mr Björn Sjöstrand (SBH, Sweden)
Starting date:
 1 January 2019
Duration: 48 months
EDCTP grant amount: EUR 7,368,180
Grant agreement: RIA2017S-2024
Scandinavian Biopharma press release

The partnership for research on Ebola vaccinations – extended follow-up and clinical research capacity build-up

Institut national de la santé et de la recherche médicale (INSERM), Paris, France with partners from France, Guinea, Mali, Sierra Leone, and the United Kingdom
Project coordinator: Prof. Yazdan Yazdanpanah (INSERM, France)
Starting date:
 1 January 2019
Duration: 66 months
EDCTP grant amount: EUR 15,884,167
Grant agreement: RIA2017S-2014

Simplified short treatment for tuberculosis

The University Court of the University of St Andrews (USTAN), St Andrews, United Kingdom with partners from Gabon, Germany, Malawi, Mozambique, the Netherlands, South Africa, Switzerland, Tanzania, Uganda, United Kingdom, and United States of America
Project coordinator: Prof. Stephen Gillespie (University of St Andrews, St Andrews, United Kingdom)
Starting date:
 1 January 2019
Duration: 48 months
EDCTP grant amount: EUR 12,000,804
Grant agreement: RIA2017S-2012

Effect of a novel typhoid conjugate vaccine in Africa: a multicentre study in Ghana and the Democratic Republic of the Congo

The Chancellor, Masters and Scholars of the University of Cambridge, Cambridge, United Kingdom, with partners from Bangladesh, Belgium, Burkina Faso, the Democratic Republic of the Congo, France, Ghana, Madagascar, South Korea, and the United States of America
Project coordinator: Dr Florian Marks (Cambridge University, United Kingdom)
Starting date:
 1 January 2019
Duration: 60 months
EDCTP grant amount: EUR 12,988,658
Grant agreement: RIA2017S-2027
Project website