The second consortium meeting of the EDCTP-funded SIMBLE project took place, like last year, in hybrid format. The SIMBLE project is a clinical diagnostic trial in Western Africa of a simplified blood culture system “the BactInsight blood culture system” to improve healthcare in low-resource settings. A delegation from Canada, Belgium, Burkina Faso, and Spain traveled to Cotonou, Benin, to meet in person on the progress of the project. Updates of the different consortium partners and work package leaders were alternated with tours of the facilities of the Cotonou partner (CHNU-PPC): laboratory, clinic, sheep farm and finally the fully installed production facility for media preparation. After a long travel at sea, the production container was installed on the premises of CNHU-PPC, and the first batch of media was produced right after the consortium meeting.