International Clinical Trials Day (20 May): the story of the VITALITY trial

We invite you to explore this very rich and insightful story by London School of Hygiene & Tropical Medicine on the VITALITY trial on protecting bone growth in children living with HIV. The story was published on the occasion of International Clinical Trials Day on which we commemorate one of the first reported, controlled clinical trials. It was carried out by James Lind in 1747 and tested six different interventions on sailors affected by scurvy. He found that oranges and lemons improved the sailors’ symptoms. It is hard to imagine a world in which we do not know the importance of vitamin C to our health.

The VITALITY project is assessing whether high-dose vitamin D and calcium carbonate supplements can protect bone and muscle development in children living with HIV. If found effective, this would provide a simple, safe and affordable intervention that could have significant benefits for people living with HIV.

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